Assessing the predictive efficacy of European-based systolic blood pressure polygenic risk scores in diverse Brazilian cohorts

Abstract Despite the identification of numerous genetic variants affecting SBP in European populations, their applicability in admixed populations remains unclear. This study evaluates the predictive efficacy of a systolic blood pressure (SBP) polygenic risk score (PRS), derived from the UK Biobank...

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Bibliographic Details
Main Authors: Samantha K. Teixeira, Fernando P. N. Rossi, José L. Patane, Jennifer M. Neyra, Ana Vitória V. Jensen, Bernardo L. Horta, Alexandre C. Pereira, Jose E. Krieger
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-79683-7
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