L-Dopa-induced changes in aperiodic bursts dynamics relate to individual clinical improvement in Parkinson’s disease

Abstract Parkinson’s disease (PD) is a neurodegenerative disease characterized by severe motor symptoms, transiently alleviated by medication (e.g. levodopa), and widespread brain activity alterations that remain poorly understood at a large scale level. To address this issue, we used resting-state...

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Main Authors: Hasnae Agouram, Matteo Neri, Marianna Angiolelli, Damien Depannemaecker, Jyotika Bahuguna, Antoine Schwey, Jean Régis, Romain Carron, Nicole Malfait, Alexandre Eusebio, Emmanuel Daucé, Pierpaolo Sorrentino
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-01024-w
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