Silencing of PCK1 mitigates the proliferation and migration of vascular smooth muscle cells and vascular intimal hyperplasia by suppressing STAT3/DRP1-mediated mitochondrial fission

Silencing of PCK1 mitigates the proliferation and migration of vascular smooth muscle cells and vascular intimal hyperplasia by suppressing STAT3/DRP1-mediated mitochondrial fission

The pathological proliferation and migration of vascular smooth muscle cells (VSMCs) are key processes during vascular neointimal hyperplasia (NIH) and restenosis. Phosphoenolpyruvate carboxy kinase 1 (PCK1) is closely related to a variety of malignant proliferative diseases. However, the role of PC...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhang Li, Chen Yingmei, Pan Quanrong, Fang Shizheng, Zhang Zhongjian, Wang Jia, Yang Yongjian, Yang Dachun, Sun Xiongshan
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-09-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
phosphoenolpyruvate carboxyl kinase 1
vascular smooth muscle cells
mitochondrial fission
neointimal hyperplasia
dynamin-related protein 1
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024154
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.sciengine.com/doi/10.3724/abbs.2024154

Similar Items