Mycobacterial genomics and structural bioinformatics: opportunities and challenges in drug discovery

Mycobacterial genomics and structural bioinformatics: opportunities and challenges in drug discovery

Of the more than 190 distinct species of Mycobacterium genus, many are economically and clinically important pathogens of humans or animals. Among those mycobacteria that infect humans, three species namely Mycobacterium tuberculosis (causative agent of tuberculosis), Mycobacterium leprae (causative...

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Bibliographic Details
Main Authors: Vaishali P. Waman, Sundeep Chaitanya Vedithi, Sherine E. Thomas, Bridget P. Bannerman, Asma Munir, Marcin J. Skwark, Sony Malhotra, Tom L. Blundell
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Emerging Microbes and Infections
Subjects:
Mycobacterium
comparative genomics
structure-guided drug discovery
drug resistance
mutation
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2018.1561158
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https://www.tandfonline.com/doi/10.1080/22221751.2018.1561158

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