Pioneering protein degradation for agricultural applications

Pioneering protein degradation for agricultural applications

Abstract As the world of agrochemicals is entering a race for efficient and safe modalities, there is an urgent and specific need for entirely new modes of action. Proteolysis-targeting chimeras (PROTACs) recruit naturally occurring E3 ubiquitin ligases to induce potent and selective degradation of...

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Main Authors: Gina L. Morgan, Hamilton Dickson, Breanna Ford, Aleksandra Noras, Steven C. Bremmer, Brian E. Watts, Joseph Pilotte, Ed Anderson, Eric D. Sullivan, Mikayla Stoner, Daniel Ouedraogo, Daniel J. Saltzberg, Karunakar R. Pothula, Paul Ingram, John Catalano, Melina Lillich, Carl-Christian Kolbe, Anne Pfeiffer, Christopher C. Ladner, Sam Gattis, Jason Speake, Stephanie Voss, Kelly Broccio, Denis Fourches
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08013-y
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https://doi.org/10.1038/s42003-025-08013-y

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