Microbiome and fragmentation pattern of blood cell-free DNA and fecal metagenome enhance colorectal cancer micro-dysbiosis and diagnosis analysis: a proof-of-concept study

Microbiome and fragmentation pattern of blood cell-free DNA and fecal metagenome enhance colorectal cancer micro-dysbiosis and diagnosis analysis: a proof-of-concept study

ABSTRACT Colorectal cancer (CRC) is the third most common cancer, and it can be prevented by performing early screening. As a hallmark of cancer, the human microbiome plays important roles in the occurrence and development of CRC. Recently, the blood microbiome has been proposed as an effective diag...

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Main Authors: Zhongkun Zhou, Yunhao Ma, Dekui Zhang, Rui Ji, Yiqing Wang, Jianfang Zhao, Chi Ma, Hongmei Zhu, Haofei Shen, Xinrong Jiang, Yuqing Niu, Juan Lu, Baizhuo Zhang, Lixue Tu, Hua Zhang, Xin Ma, Peng Chen
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mSystems
Subjects:
microbiome
cell-free DNA
colorectal cancer
diagnosis
fragmentation pattern
Online Access:https://journals.asm.org/doi/10.1128/msystems.00276-25
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https://journals.asm.org/doi/10.1128/msystems.00276-25

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