PPARα deficiency exacerbates retinal pathological changes and dysfunction in high-fat diet mice

AIM: To examined the effects of a high-fat diet (HFD) on retinal pathological changes and dysfunction using peroxisome proliferator-activated receptor-alpha (PPARα) knockout mice. METHODS: For four months, C57BL/6J and PPARα knockout mice received either HFD or a standard diet (SD). A fluorometric m...

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Bibliographic Details
Main Authors: Xue Wang, Jing-Jing Ding, Chao-Feng Yu, Deng-Cheng Xiao, Li-Ming Tao, Zheng-Xuan Jiang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2025-06-01
Series:International Journal of Ophthalmology
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Online Access:http://ies.ijo.cn/en_publish/2025/6/20250603.pdf
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