An assay of human tyrosine protein kinase ABL activity using an Escherichia coli protein expression system

ABL, a human tyrosine protein kinase, and its substrate are co-expressed in Escherichia coli. Tyrosine phosphorylation of the substrate in E. coli was detected using Phos-tag SDS-PAGE. The bacterial co-expression system was used as a field for the kinase reaction to evaluate the enzymatic activity o...

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Bibliographic Details
Main Authors: Emiko Kinoshita-Kikuta, Momoka Yoshimoto, Marina Yano, Eiji Kinoshita, Tohru Koike
Format: Article
Language:English
Published: Taylor & Francis Group 2021-04-01
Series:BioTechniques
Subjects:
Online Access:https://www.future-science.com/doi/10.2144/btn-2020-0154
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