Hypoxia- and lactate metabolism-associated prognostic and therapeutic signature in pancreatic cancer

Abstract Background Hypoxia and lactate metabolism products are critical components of the tumor microenvironment in pancreatic cancer (PC), influencing tumor invasiveness, metastasis, and treatment resistance. This study aims to explore the role of hypoxia- and lactate metabolism-related genes (HLR...

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Bibliographic Details
Main Authors: Chen-Hui Zhang, An-Qi Huang, Cang-Chang Shi, Zhi-Jia Jiang, Hao Yao, Jin-Jin Sun
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-025-02873-w
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