CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane‐induced alopecia

Abstract Taxanes are a leading cause of severe and often permanent chemotherapy‐induced alopecia. As the underlying pathobiology of taxane chemotherapy‐induced alopecia remains poorly understood, we investigated how paclitaxel and docetaxel damage human scalp hair follicles in a clinically relevant...

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Bibliographic Details
Main Authors: Talveen S Purba, Kayumba Ng'andu, Lars Brunken, Eleanor Smart, Ellen Mitchell, Nashat Hassan, Aaron O'Brien, Charlotte Mellor, Jennifer Jackson, Asim Shahmalak, Ralf Paus
Format: Article
Language:English
Published: Springer Nature 2019-09-01
Series:EMBO Molecular Medicine
Subjects:
Online Access:https://doi.org/10.15252/emmm.201911031
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