The Genetic Fingerprint of HIV in the Brain: Insights into Neurocognitive Dysfunction
HIV, primarily targeting CD4 cells, infiltrates the CNS through various mechanisms, including chemokine-mediated signaling and blood–brain barrier disruption, leading to neuroinflammation and neuronal dysfunction. Viral proteins such as gp120, Tat, and Vpr directly induce neurotoxicity, oxidative st...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-06-01
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| Series: | Neuroglia |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2571-6980/6/2/23 |
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