Disruption of Type I Interferon Induction by HIV Infection of T Cells.

Disruption of Type I Interferon Induction by HIV Infection of T Cells.

Our main objective of this study was to determine how Human Immunodeficiency Virus (HIV) avoids induction of the antiviral Type I Interferon (IFN) system. To limit viral infection, the innate immune system produces important antiviral cytokines such as the IFN. IFN set up a critical roadblock to vir...

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Main Authors: David Jesse Sanchez, Daniel Miranda, Matthew D Marsden, Thomas Michael A Dizon, Johnny R Bontemps, Sergio J Davila, Lara E Del Mundo, Thai Ha, Ashkon Senaati, Jerome A Zack, Genhong Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0137951
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https://doi.org/10.1371/journal.pone.0137951

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