Transcriptome remodelling and changes in growth and cardiometabolic phenotype result following Grb10a knockdown in the early life of the zebrafish
Abstract Embryonic growth trajectory is a risk factor for chronic metabolic and cardiovascular disorders. Grb10 is a negative regulator of the main pathways driving embryonic growth. This study has characterised growth, cardiometabolic status, and the impact on co-ordination of gene expression follo...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-07-01
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| Series: | Cellular and Molecular Life Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s00018-025-05784-9 |
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