Gintonin Binds to Reduced LPA4 Receptor Subtype in Human Cortical Neurons in Alzheimer’s Disease Brains

Gintonin Binds to Reduced LPA4 Receptor Subtype in Human Cortical Neurons in Alzheimer’s Disease Brains

Ginseng, a traditional herbal medicine with a long history of use, is known to support human health, particularly by influencing brain function. Recent studies have identified gintonin, a lysophosphatidic acid (LPA) receptor ligand derived from ginseng, as a key bioactive. However, the specific LPA...

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Bibliographic Details
Main Authors: Kyu-Sung Kim, Rami Lee, Inyeong Park, Sung-Hee Hwang, Yeshin Kim, Jae-Won Jang, Hyung-Seok Kim, Seong-Min Choi, Sang Jin Kim, Hwa Jin Cho, Ik-Hyun Cho, Jong-Hoon Kim, Do-Geun Kim, Seung-Yeol Nah
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biomolecules
Subjects:
ginseng
gintonin
LPA4 receptor
human cortex
AD prevention
Online Access:https://www.mdpi.com/2218-273X/15/2/179
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