DNFE: Directed network flow entropy for detecting tipping points during biological processes.
Typically, in dynamic biological processes, there is a critical state or tipping point that marks the transition from one stable state to another, surpassing which a considerable qualitative shift takes place. Identifying this tipping point and its driving network is essential to avert or delay disa...
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| Main Authors: | Xueqing Peng, Rui Qiao, Peiluan Li, Luonan Chen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-07-01
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| Series: | PLoS Computational Biology |
| Online Access: | https://doi.org/10.1371/journal.pcbi.1013336 |
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