Prediction of PD-L1 tumor positive score in lung squamous cell carcinoma with H&E staining images and deep learning

Prediction of PD-L1 tumor positive score in lung squamous cell carcinoma with H&E staining images and deep learning

BackgroundDetecting programmed death ligand 1 (PD-L1) expression based on immunohistochemical (IHC) staining is an important guide for the treatment of lung cancer with immune checkpoint inhibitors. However, this method has problems such as high staining costs, tumor heterogeneity, and subjective di...

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Bibliographic Details
Main Authors: Qiushi Wang, Xixiang Deng, Pan Huang, Qiang Ma, Lianhua Zhao, Yangyang Feng, Yiying Wang, Yuan Zhao, Yan Chen, Peng Zhong, Peng He, Mingrui Ma, Peng Feng, Hualiang Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Artificial Intelligence
Subjects:
lung squamous cell carcinoma
PD-L1
deep learning
TransUnet
H&E staining
Online Access:https://www.frontiersin.org/articles/10.3389/frai.2024.1452563/full
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https://www.frontiersin.org/articles/10.3389/frai.2024.1452563/full

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