In Silico Evaluation of Novel 2-Pyrazoline Carboxamide Derivatives as Potential Protease Inhibitors Against <i>Plasmodium</i> Parasites

In Silico Evaluation of Novel 2-Pyrazoline Carboxamide Derivatives as Potential Protease Inhibitors Against <i>Plasmodium</i> Parasites

Malaria, a devastating disease caused by <i>Plasmodium</i> parasites, continues to pose a significant threat to global health, with increasing resistance to current antimalarial drugs. In this study, we employed an in silico approach to design and evaluate novel 2-pyrazoline carboxamide...

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Bibliographic Details
Main Authors: Yusuf Jimoh, Idris Yunusa Abdullah, Asmau Nasir Hamza, Maryam Abdullahi, Jibril Ahmadu, Lukman Ali Hassan, Muhammad Shamsudeen Yakubu, Zukhruf Salami
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Chemistry Proceedings
Subjects:
antimalarial
computational chemistry
in silico
<i>Plasmodium falciparum</i>
protease inhibitors
pyrazoline
Online Access:https://www.mdpi.com/2673-4583/16/1/57
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