Pre-ciliated tubal epithelial cells are prone to initiation of high-grade serous ovarian carcinoma

Pre-ciliated tubal epithelial cells are prone to initiation of high-grade serous ovarian carcinoma

Abstract The distal region of the uterine (Fallopian) tube is commonly associated with high-grade serous carcinoma (HGSC), the predominant and most aggressive form of ovarian or extra-uterine cancer. Specific cell states and lineage dynamics of the adult tubal epithelium (TE) remain insufficiently u...

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Main Authors: Andrea Flesken-Nikitin, Coulter Q. Ralston, Dah-Jiun Fu, Andrea J. De Micheli, Daryl J. Phuong, Blaine A. Harlan, Christopher S. Ashe, Amanda P. Armstrong, David W. McKellar, Sangeeta Ghuwalewala, Lora H. Ellenson, John C. Schimenti, Benjamin D. Cosgrove, Alexander Yu. Nikitin
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-52984-1
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https://doi.org/10.1038/s41467-024-52984-1

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