Ligands of the Mitochondrial 18 kDa Translocator Protein Attenuate Apoptosis of Human Glioblastoma Cells Exposed to Erucylphosphohomocholine
Background: We have previously shown that the anti-neoplastic agent erucylphosphohomocholine (ErPC3) requires the mitochondrial 18 kDa Translocator protein (TSPO), formerly known as the peripheral-type benzodiazepine receptor (PBR), to induce cell death via the mitochondrial apoptosis pathway.
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| Main Authors: | Wilfried Kugler, Leo Veenman, Yulia Shandalov, Svetlana Leschiner, Ilana Spanier, Max Lakomek, Moshe Gavish |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2008-01-01
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| Series: | Cellular Oncology |
| Online Access: | http://dx.doi.org/10.3233/CLO-2008-0431 |
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