Ligands of the Mitochondrial 18 kDa Translocator Protein Attenuate Apoptosis of Human Glioblastoma Cells Exposed to Erucylphosphohomocholine

Background: We have previously shown that the anti-neoplastic agent erucylphosphohomocholine (ErPC3) requires the mitochondrial 18 kDa Translocator protein (TSPO), formerly known as the peripheral-type benzodiazepine receptor (PBR), to induce cell death via the mitochondrial apoptosis pathway.

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Bibliographic Details
Main Authors: Wilfried Kugler, Leo Veenman, Yulia Shandalov, Svetlana Leschiner, Ilana Spanier, Max Lakomek, Moshe Gavish
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.3233/CLO-2008-0431
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