The effect of parenteral vitamin B12 treatment on its plasma metabolomic profile and on functional biomarkers of its deficiency

The effect of parenteral vitamin B12 treatment on its plasma metabolomic profile and on functional biomarkers of its deficiency

Abstract Diagnosis of vitamin B12 (B12) deficiency is hampered by the low specificity cut-offs of blood-based biomarkers, like serum B12 and holo-transcobalamin (HoloTc), or B12-associated metabolites like methylmalonic acid (MMA) and homocysteine (Hcy) concentrations, or their combinations computed...

Full description

Saved in:
Bibliographic Details
Main Authors: Sarita Devi, Roshni M. Pasanna, Fathima Ayoob, Harshpal Singh Sachdev, Tinku Thomas, Oliver Fiehn, Anura V. Kurpad
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Vitamin B12
Stable isotope
Functional deficiency
Breath test
Metabolomics
Online Access:https://doi.org/10.1038/s41598-025-09110-y
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-09110-y

Similar Items