Multi-analyte approach combining cfDNA sequencing and protein testing for early ovarian cancer detection

Multi-analyte approach combining cfDNA sequencing and protein testing for early ovarian cancer detection

Summary: Non-invasive liquid biopsy is a promising strategy for ovarian cancer (OC) detection. We evaluated the feasibility and efficacy of a multi-analyte approach combining circulating tumor DNA (ctDNA) detection with protein biomarkers for early OC detection. At 95% specificity, CA125 and ctDNA a...

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Bibliographic Details
Main Authors: Fenfen Wang, Lingfang Wang, Ziyu Xing, Lingjia Lu, Zhuoqun Lin, Senmi Qian, Tao Zhu, Zhuyan Shao, Lingjun Zhao, Jie Dong, Fangfang Qian, Yang Li, Xiaojing Chen, Siqi Yang, Xiaodong Cheng
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:iScience
Subjects:
Health sciences
Medicine
Medical specialty
Internal medicine
Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225008788
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http://www.sciencedirect.com/science/article/pii/S2589004225008788

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