The chemokine MIP1alpha/CCL3 determines pathology in primary RSV infection by regulating the balance of T cell populations in the murine lung.

The chemokine MIP1alpha/CCL3 determines pathology in primary RSV infection by regulating the balance of T cell populations in the murine lung.

<h4>Background</h4>CD8 T cells assist in the clearance of respiratory syncytial virus (RSV) infection from the lungs. However, disease after RSV infection is in part caused by excessive T cell activity, and a balance is therefore needed between beneficial and harmful cellular immune resp...

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Bibliographic Details
Main Authors: John S Tregoning, Philippa K Pribul, Alasdair M J Pennycook, Tracy Hussell, Belinda Wang, Nicholas Lukacs, Jurgen Schwarze, Fiona J Culley, Peter J M Openshaw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009381&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009381&type=printable

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