Population pharmacokinetics modelling for clinical dose adjustment of carboplatin in dogs

Abstract Background Carboplatin is a human chemotherapeutic agent which is frequently used in dogs for the management of solid tumors. In human patient, its dosage is adjusted carefully, based on the creatinine clearance computation. In dogs however, the pharmacokinetics of carboplatin is poorly kno...

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Bibliographic Details
Main Authors: Jérémy Béguin, Sarra Mahfoudhi, Marie Uzel, Antoine Rostang, Catherine Ibish, Aude A. Ferran, Ludovic Pelligand, Anne Hulin, Matthias Kohlhauer
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Veterinary Research
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Online Access:https://doi.org/10.1186/s12917-024-04404-1
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