Hippo pathway activation mediates cardiomyocyte ferroptosis to promote dilated cardiomyopathy through downregulating NFS1
Cardiomyocyte loss by regulated death modes, like apoptosis and ferroptosis, has been implicated in the development of dilated cardiomyopathy (DCM). It remains unclear whether cardiomyocyte ferroptosis occurs as a consequence of Hippo pathway activation. Using a mouse model of DCM by overexpression...
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| Main Authors: | Gang She, Xia-Xia Hai, Li-Ye Jia, Yong-Jian Zhang, Yu-Jie Ren, Zheng-Da Pang, Lin-Hong Wu, Meng-Zhuan Han, Yu Zhang, Jing-Jing Li, Ru-Yue Bai, Bao-Chang Lai, Yi-Yi Yang, Junichi Sadoshima, Xiao-Jun Du, Xiu-Ling Deng, Yi Zhang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
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| Series: | Redox Biology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231725001107 |
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