Cardiac Glycosides: From Natural Defense Molecules to Emerging Therapeutic Agents

Cardiac Glycosides: From Natural Defense Molecules to Emerging Therapeutic Agents

Cardiac glycosides (CGs), a class of plant- and animal-derived compounds historically used to treat heart failure, have garnered renewed interest for their diverse pharmacological properties beyond Na<sup>+</sup>/K<sup>+</sup>-ATPase (NKA) inhibition. Recent studies reveal th...

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Bibliographic Details
Main Authors: Arturo Ponce, Catalina Flores-Maldonado, Ruben G. Contreras
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomolecules
Subjects:
cardiac glycosides
Na<sup>+</sup>/K<sup>+</sup>-ATPase
signal transduction pathways
cancer therapy
antiviral agents
drug repurposing
Online Access:https://www.mdpi.com/2218-273X/15/6/885
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