Effect of knee extension constraint training on walking biomechanics 6 months after anterior cruciate ligament reconstruction: a double-blind randomized controlled clinical trial

Abstract Background The incidence of knee osteoarthritis after anterior cruciate ligament reconstruction (ACLR) is high to 57%, and the biomechanical abnormality during walking is one of the reasons. The purpose of this study was to investigate the effect of 12 weeks of knee extension constraint tra...

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Main Authors: Tianyu Gao, Hongshi Huang, Yuanyuan Yu, Hui Liu, Yingfang Ao
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-024-05447-8
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author Tianyu Gao
Hongshi Huang
Yuanyuan Yu
Hui Liu
Yingfang Ao
author_facet Tianyu Gao
Hongshi Huang
Yuanyuan Yu
Hui Liu
Yingfang Ao
author_sort Tianyu Gao
collection DOAJ
description Abstract Background The incidence of knee osteoarthritis after anterior cruciate ligament reconstruction (ACLR) is high to 57%, and the biomechanical abnormality during walking is one of the reasons. The purpose of this study was to investigate the effect of 12 weeks of knee extension constraint training on walking biomechanics during the stance phase of injured side after ACLR. Methods Forty-five patients were randomly assigned to three groups based on different brace conditions from 13 weeks to 24 weeks after ACLR: experimental (brace with knee extension constraint), placebo (brace without knee extension constraint), and control (no brace). Gait analysis was performed 3 and 6 months after ACLR. The peak for knee flexion angle (KFA), knee extension moment (KEM), and vertical ground reaction force (vGRF) were compared by 2 (time) x 3 (group) repeated-measures analysis of covariance (ANCOVA), and pairwise comparisons were conducted. . Results There was a significant time x group interaction for the peak KFA (p = 0.047), and there was no significant time x group interaction for the peak KEM and peak vGRF. The pairwise comparisons showed that there were no statistical differences among the groups both the pre-intervention and post-intervention in the peak KFA, peak KEM, and peak vGRF. Compared with pre-intervention, the peak vGRF in the experimental group was significantly greater (p = 0.009) and the peak KFA in the control group was significantly lower (p = 0.041) post-intervention. There were not significantly different in the placebo group between pre-intervention and post-intervention. Conclusion 12 weeks of knee extension constraint training can increase lower extremity loading on the injured side, may be a potential therapeutic adjunct to improve abnormal gait after ACLR.
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spelling doaj-art-8ff1196460c7437f8486ec236f1d63892025-01-12T12:32:41ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2025-01-0120111110.1186/s13018-024-05447-8Effect of knee extension constraint training on walking biomechanics 6 months after anterior cruciate ligament reconstruction: a double-blind randomized controlled clinical trialTianyu Gao0Hongshi Huang1Yuanyuan Yu2Hui Liu3Yingfang Ao4Department of Sports Medicine, Beijing Key Laboratory of Sports Injuries, Engineering Research Center of Sports Trauma Treatment Technology and Devices, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Ministry of EducationDepartment of Sports Medicine, Beijing Key Laboratory of Sports Injuries, Engineering Research Center of Sports Trauma Treatment Technology and Devices, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Ministry of EducationDepartment of Sports Medicine, Beijing Key Laboratory of Sports Injuries, Engineering Research Center of Sports Trauma Treatment Technology and Devices, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Ministry of EducationBiomechanics Laboratory, College of Human Movement Science, Beijing Sport UniversityDepartment of Sports Medicine, Beijing Key Laboratory of Sports Injuries, Engineering Research Center of Sports Trauma Treatment Technology and Devices, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Ministry of EducationAbstract Background The incidence of knee osteoarthritis after anterior cruciate ligament reconstruction (ACLR) is high to 57%, and the biomechanical abnormality during walking is one of the reasons. The purpose of this study was to investigate the effect of 12 weeks of knee extension constraint training on walking biomechanics during the stance phase of injured side after ACLR. Methods Forty-five patients were randomly assigned to three groups based on different brace conditions from 13 weeks to 24 weeks after ACLR: experimental (brace with knee extension constraint), placebo (brace without knee extension constraint), and control (no brace). Gait analysis was performed 3 and 6 months after ACLR. The peak for knee flexion angle (KFA), knee extension moment (KEM), and vertical ground reaction force (vGRF) were compared by 2 (time) x 3 (group) repeated-measures analysis of covariance (ANCOVA), and pairwise comparisons were conducted. . Results There was a significant time x group interaction for the peak KFA (p = 0.047), and there was no significant time x group interaction for the peak KEM and peak vGRF. The pairwise comparisons showed that there were no statistical differences among the groups both the pre-intervention and post-intervention in the peak KFA, peak KEM, and peak vGRF. Compared with pre-intervention, the peak vGRF in the experimental group was significantly greater (p = 0.009) and the peak KFA in the control group was significantly lower (p = 0.041) post-intervention. There were not significantly different in the placebo group between pre-intervention and post-intervention. Conclusion 12 weeks of knee extension constraint training can increase lower extremity loading on the injured side, may be a potential therapeutic adjunct to improve abnormal gait after ACLR.https://doi.org/10.1186/s13018-024-05447-8Anterior cruciate ligament reconstructionBiomechanicsRehabilitationWalking
spellingShingle Tianyu Gao
Hongshi Huang
Yuanyuan Yu
Hui Liu
Yingfang Ao
Effect of knee extension constraint training on walking biomechanics 6 months after anterior cruciate ligament reconstruction: a double-blind randomized controlled clinical trial
Journal of Orthopaedic Surgery and Research
Anterior cruciate ligament reconstruction
Biomechanics
Rehabilitation
Walking
title Effect of knee extension constraint training on walking biomechanics 6 months after anterior cruciate ligament reconstruction: a double-blind randomized controlled clinical trial
title_full Effect of knee extension constraint training on walking biomechanics 6 months after anterior cruciate ligament reconstruction: a double-blind randomized controlled clinical trial
title_fullStr Effect of knee extension constraint training on walking biomechanics 6 months after anterior cruciate ligament reconstruction: a double-blind randomized controlled clinical trial
title_full_unstemmed Effect of knee extension constraint training on walking biomechanics 6 months after anterior cruciate ligament reconstruction: a double-blind randomized controlled clinical trial
title_short Effect of knee extension constraint training on walking biomechanics 6 months after anterior cruciate ligament reconstruction: a double-blind randomized controlled clinical trial
title_sort effect of knee extension constraint training on walking biomechanics 6 months after anterior cruciate ligament reconstruction a double blind randomized controlled clinical trial
topic Anterior cruciate ligament reconstruction
Biomechanics
Rehabilitation
Walking
url https://doi.org/10.1186/s13018-024-05447-8
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