SKI regulates rRNA transcription and pericentromeric heterochromatin to ensure centromere integrity and genome stability
Accurate chromosome segregation and ribosomal gene expression silencing are essential for maintaining genome integrity, and disruptions in these processes are key for oncogenesis and cancer progression. Here, we demonstrate a novel role for the transcriptional co-repressor SKI in regulating rDNA and...
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| Main Authors: | Víctor Pola-Véliz, David Carrero, Eduardo A. Sagredo, Víctor Inostroza, Claudio Cappelli, Solange Rivas, Mirit Bitrán, Evelyn Zambrano, Evelin Gonzalez, Fernanda Morales, Marcia Manterola, Martín Montecino, Ricardo Armisén, Katherine Marcelain |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | Neoplasia: An International Journal for Oncology Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558625000843 |
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