Emerin deficiency drives MCF7 cells to an invasive phenotype

Abstract During metastasis, cancer cells traverse the vasculature by squeezing through very small gaps in the endothelium. Thus, nuclei in metastatic cancer cells must become more malleable to move through these gaps. Our lab showed invasive breast cancer cells have 50% less emerin protein resulting...

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Bibliographic Details
Main Authors: Emily Hansen, Christal Rolling, Matthew Wang, James M. Holaska
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-70752-5
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