In Vivo Noninvasive Optical Imaging of Receptor-Mediated RGD Internalization Using Self-Quenched Cy5-Labeled RAFT-c(-RGDfK-)

In Vivo Noninvasive Optical Imaging of Receptor-Mediated RGD Internalization Using Self-Quenched Cy5-Labeled RAFT-c(-RGDfK-)

We reported that regioselectively addressable functionalized template (RAFT)-c(-RGDfK-) 4 presenting four cyclic (Arg-Gly-Asp) (cRGD) peptides targets integrin a V b 3 with an improved specificity compared with monomeric cRGD. In this study, we improved this vector by creating a “stealth” molecule i...

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Bibliographic Details
Main Authors: Zhao-Hui Jin, Jesus Razkin, Veronique Josserand, Didier Boturyn, Alexeï Grichine, Isabelle Texier, Marie-Christine Favrot, Pascal Dumy, Jean-Luc Coll
Format: Article
Language:English
Published: SAGE Publishing 2007-01-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2007.00002
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https://doi.org/10.2310/7290.2007.00002

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