Modulatory Effect of Cucurbitacin D from <i>Elaeocarpus hainanensis</i> on ZNF217 Oncogene Expression in NPM-Mutated Acute Myeloid Leukemia

Modulatory Effect of Cucurbitacin D from <i>Elaeocarpus hainanensis</i> on ZNF217 Oncogene Expression in NPM-Mutated Acute Myeloid Leukemia

<b>Background/Objectives:</b> The expression of oncogene zinc-finger protein 217 (ZNF217) has been reported to play a central role in cancer development, resistance, and recurrence. Therefore, targeting ZNF217 has been proposed as a possible strategy to fight cancer, and there has been m...

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Main Authors: Sabrina Adorisio, Alessandra Fierabracci, Ba Thi Cham, Vu Dinh Hoang, Nguyen Thi Thuy Linh, Le Thi Hong Nhung, Maria Paola Martelli, Emira Ayroldi, Simona Ronchetti, Lucrezia Rosati, Silvia Di Giacomo, Trinh Thi Thuy, Domenico Vittorio Delfino
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceuticals
Subjects:
<i>Elaeocarpus hainanensis</i>
cucurbitacin D
ZNF217
nucleophosmin
acute myeloid leukemia
Online Access:https://www.mdpi.com/1424-8247/17/12/1561
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