Immunohistochemical expression of smoothened in periocular basal cell, squamous cell and sebaceous carcinomas

Abstract Inhibition of Smoothened (SMO), a key protein in the Hedgehog signaling pathway, is effective for locally advanced basal cell carcinoma (BCC), but is not yet used for sebaceous carcinoma (SEB) or squamous cell carcinoma (SCC). This study quantified SMO expression and its relationship to pro...

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Bibliographic Details
Main Authors: Gustav Stålhammar, Basel Haj Hasan, Krzysztof W. Kotowski, Elin Bohman, Emma Lardner, Alexander Berg Rendahl
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-06011-y
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