Network pharmacology to explore the novel anti-inflammatory mechanism of naringenin in intestinal ischemia/reperfusion injury

Network pharmacology to explore the novel anti-inflammatory mechanism of naringenin in intestinal ischemia/reperfusion injury

IntroductionNaringenin (Nar), a common flavanone abundant in citrus fruits and tomatoes, is common in diets. Although Nar can alleviate intestinal ischemia/reperfusion injury (IRI), the exact anti-inflammatory mechanisms are unclear and require further study.MethodsIn this study, we employed a compr...

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Bibliographic Details
Main Authors: Min Hou, Yanshun Wang, Suheng Chen, Zhiguo Tan, Jie Liu, Xiaoxi Li, Xiaoxia Han, Zaiqi Yang, Yufang Leng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
intestinal ischemia/reperfusion injury
network pharmacology
naringenin
inflammation
YAP
stat3
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1623080/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1623080/full

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