Deep transcranial ultrasound stimulation using personalized acoustic metamaterials improves treatment-resistant depression in humans

Background: Neuromodulation of deep brain regions has shown promise for treatment-resistant depression (TRD). However, it currently requires neurosurgical electrode implantation, posing significant risks and limiting widespread use while TRD affects around 100 million people worldwide. Low-intensity...

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Bibliographic Details
Main Authors: David Attali, Thomas Tiennot, Thomas J. Manuel, Maxime Daniel, Alexandre Houdouin, Philippe Annic, Alexandre Dizeux, Alexandre Haroche, Ghita Dadi, Adèle Henensal, Mylène Moyal, Alice Le Berre, Cécile Paolillo, Sylvain Charron, Clément Debacker, Maliesse Lui, Sabrina Lekcir, Rosella Mancusi, Thierry Gallarda, Tarek Sharshar, Khaoussou Sylla, Catherine Oppenheim, Arnaud Cachia, Mickael Tanter, Jean-Francois Aubry, Marion Plaze
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Brain Stimulation
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Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X25000993
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