Diversity of clustered protocadherin-α genes in neuronal identity and its role in short-term specific associative memory formation

Abstract Clustered protocadherins (cPcdh) are cell adhesion molecules with 58 isoforms, essential for neural circuit formation and higher cognitive functions. This study investigated the impact of reduced cPcdh-α diversity on cognitive function using mutant mice. Behavioral tests revealed that cPcdh...

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Bibliographic Details
Main Authors: Tomoki Osuka, Hiroki Yamamoto, Takeshi Yagi
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-02546-2
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