Engine breakdown of lysosomes and related organelles and the resulting physiology

Late endosomes/lysosomes (LE/Lys) and lysosome related organelles (LROs) move dynamically through cells which involves many levels of regulation. To reach their destination, they need to connect to the motor proteins dynein-dynactin, kinesin or myosin for long-range bidirectional transport along mic...

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Bibliographic Details
Main Authors: Nina Bakker, Marlieke L. M. Jongsma, Jacques Neefjes
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1575571/full
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