Effects and moderator of high-intensity interval training and moderate-intensity continuous training among children and adolescents with overweight or obese: a systematic review and meta-analysis

ObjectivesThis meta-analysis aimed to synthesize current evidence and address inconsistencies in the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on children and adolescents with overweight or obesity. We sought to: (1) assess the effects of HI...

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Main Authors: Weihua Zheng, Mingyue Yin, Yan Guo, Haiyang Liu, Jiaxin Sun, Ao Zhu, Yuming Zhong, Kai Xu, Hansen Li, Shunzhe Piao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1625516/full
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author Weihua Zheng
Mingyue Yin
Yan Guo
Haiyang Liu
Jiaxin Sun
Ao Zhu
Yuming Zhong
Kai Xu
Hansen Li
Shunzhe Piao
author_facet Weihua Zheng
Mingyue Yin
Yan Guo
Haiyang Liu
Jiaxin Sun
Ao Zhu
Yuming Zhong
Kai Xu
Hansen Li
Shunzhe Piao
author_sort Weihua Zheng
collection DOAJ
description ObjectivesThis meta-analysis aimed to synthesize current evidence and address inconsistencies in the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on children and adolescents with overweight or obesity. We sought to: (1) assess the effects of HIIT and MICT versus non-exercise controls; (2) compare HIIT and MICT directly; and (3) identify potential moderators through subgroup analyses.MethodsSystematic searches were conducted in PubMed, Web of Science, China National Knowledge Infrastructure, and CSTJ. Standardized mean differences (SMD) were calculated using a random-effects model. Subgroup and sensitivity analyses explored potential moderators.ResultsA total of 26 moderate-to-high-quality studies (Randomized controlled trials and non-RCT) involving 1,078 participants (765 males, 313 females; aged 9–19) were included. Compared with controls, HIIT significantly reduced fat mass (SMD = −0.69), waistline (SMD = −0.67), body weight (SMD = −0.81), diastolic blood pressure (diastolic blood pressure, SMD = −0.68), and improved VO2max (SMD = 2.06). moderate-intensity continuous training showed significant effects on BMI (SMD = −1.58), body weight (SMD = −0.59), DBP (SMD = −0.60), and VO2max (SMD = 1.26). HIIT outperformed MICT in improving VO2max (SMD = 0.81) and reducing systolic blood pressure (systolic blood pressure, SMD = −0.51). Subgroup analyses showed that HIIT yielded greater benefits than MICT in improving VO2max among overweight children, reducing SBP in obese male adolescents, and in programs involving more than three sessions per week.ConclusionHIIT was more effective than MICT in improving VO2max and reducing SBP, especially in specific subgroups. Running-based HIIT three times per week is recommended, while cycling may offer a safer alternative. Results should be interpreted cautiously due to limited subgroup data and potential bias.Prospero RegistrationCRD42024612098.
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publisher Frontiers Media S.A.
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series Frontiers in Physiology
spelling doaj-art-8f3c483850124b36833958bcb8b3cf192025-08-20T03:09:35ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2025-07-011610.3389/fphys.2025.16255161625516Effects and moderator of high-intensity interval training and moderate-intensity continuous training among children and adolescents with overweight or obese: a systematic review and meta-analysisWeihua Zheng0Mingyue Yin1Yan Guo2Haiyang Liu3Jiaxin Sun4Ao Zhu5Yuming Zhong6Kai Xu7Hansen Li8Shunzhe Piao9School of Social Sports, Shenyang Sport University, Shengyang, ChinaSchool of Athletic Performance, Shanghai University of Sport, Shanghai, ChinaSport Institute, Hua Qiao University, Quanzhou, ChinaSchool of Social Sports, Shenyang Sport University, Shengyang, ChinaSchool of Social Sports, Shenyang Sport University, Shengyang, ChinaSchool of Social Sports, Shenyang Sport University, Shengyang, ChinaSchool of Athletic Performance, Shanghai University of Sport, Shanghai, ChinaSchool of Athletic Performance, Shanghai University of Sport, Shanghai, ChinaSchool of Physical Education, Sichuan Agricultural University, Ya’an, ChinaSchool of Social Sports, Shenyang Sport University, Shengyang, ChinaObjectivesThis meta-analysis aimed to synthesize current evidence and address inconsistencies in the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on children and adolescents with overweight or obesity. We sought to: (1) assess the effects of HIIT and MICT versus non-exercise controls; (2) compare HIIT and MICT directly; and (3) identify potential moderators through subgroup analyses.MethodsSystematic searches were conducted in PubMed, Web of Science, China National Knowledge Infrastructure, and CSTJ. Standardized mean differences (SMD) were calculated using a random-effects model. Subgroup and sensitivity analyses explored potential moderators.ResultsA total of 26 moderate-to-high-quality studies (Randomized controlled trials and non-RCT) involving 1,078 participants (765 males, 313 females; aged 9–19) were included. Compared with controls, HIIT significantly reduced fat mass (SMD = −0.69), waistline (SMD = −0.67), body weight (SMD = −0.81), diastolic blood pressure (diastolic blood pressure, SMD = −0.68), and improved VO2max (SMD = 2.06). moderate-intensity continuous training showed significant effects on BMI (SMD = −1.58), body weight (SMD = −0.59), DBP (SMD = −0.60), and VO2max (SMD = 1.26). HIIT outperformed MICT in improving VO2max (SMD = 0.81) and reducing systolic blood pressure (systolic blood pressure, SMD = −0.51). Subgroup analyses showed that HIIT yielded greater benefits than MICT in improving VO2max among overweight children, reducing SBP in obese male adolescents, and in programs involving more than three sessions per week.ConclusionHIIT was more effective than MICT in improving VO2max and reducing SBP, especially in specific subgroups. Running-based HIIT three times per week is recommended, while cycling may offer a safer alternative. Results should be interpreted cautiously due to limited subgroup data and potential bias.Prospero RegistrationCRD42024612098.https://www.frontiersin.org/articles/10.3389/fphys.2025.1625516/fullHIIT (high intensity interval training)MICTchildrenadolescentbody shapecardiopulmonary health
spellingShingle Weihua Zheng
Mingyue Yin
Yan Guo
Haiyang Liu
Jiaxin Sun
Ao Zhu
Yuming Zhong
Kai Xu
Hansen Li
Shunzhe Piao
Effects and moderator of high-intensity interval training and moderate-intensity continuous training among children and adolescents with overweight or obese: a systematic review and meta-analysis
Frontiers in Physiology
HIIT (high intensity interval training)
MICT
children
adolescent
body shape
cardiopulmonary health
title Effects and moderator of high-intensity interval training and moderate-intensity continuous training among children and adolescents with overweight or obese: a systematic review and meta-analysis
title_full Effects and moderator of high-intensity interval training and moderate-intensity continuous training among children and adolescents with overweight or obese: a systematic review and meta-analysis
title_fullStr Effects and moderator of high-intensity interval training and moderate-intensity continuous training among children and adolescents with overweight or obese: a systematic review and meta-analysis
title_full_unstemmed Effects and moderator of high-intensity interval training and moderate-intensity continuous training among children and adolescents with overweight or obese: a systematic review and meta-analysis
title_short Effects and moderator of high-intensity interval training and moderate-intensity continuous training among children and adolescents with overweight or obese: a systematic review and meta-analysis
title_sort effects and moderator of high intensity interval training and moderate intensity continuous training among children and adolescents with overweight or obese a systematic review and meta analysis
topic HIIT (high intensity interval training)
MICT
children
adolescent
body shape
cardiopulmonary health
url https://www.frontiersin.org/articles/10.3389/fphys.2025.1625516/full
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