Lead-induced actin polymerization aggravates neutrophil extracellular trap formation and contributes to vascular inflammation

Lead-induced actin polymerization aggravates neutrophil extracellular trap formation and contributes to vascular inflammation

Lead (Pb) exposure is widely acknowledged as a risk factor for cardiovascular diseases. Previous studies have established neutrophil involvement in Pb-induced cardiovascular injuries; however, the underlying mechanisms remain unclear. To address this knowledge gap, the binding targets of Pb in neutr...

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Main Authors: Qiying Nong, Yanjun Wu, Suhui Liu, Yinyin Tang, Jiayun Wu, Hongmei Huang, Jiaying Hong, Yiru Qin, Ruimei Xu, Wenxia Zhao, Baowei Chen, Zhenlie Huang, Ligang Hu, Na Zhao, Yongshun Huang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Heavy metal
Actin polymerization
Neutrophil extracellular trap
Cardiovascular injury
Hypertension
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324016749
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