Engineering a controlled cardiac multilineage co-differentiation process using statistical design of experiments
Abstract Background The heart is a complex organ composed of diverse cell types, whose interplay is crucial for development, tissue homeostasis, and disease progression. A potential approach to recapitulate this heterotypic multicellular environment is the co-differentiation of induced pluripotent s...
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| Main Authors: | Hirokazu Akiyama, Yosuke Katayama, Kazunori Shimizu, Hiroyuki Honda |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
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| Series: | Stem Cell Research & Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13287-025-04408-0 |
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