Mendelian randomization provides a multi-omics perspective on the regulation of genes involved in ribosome biogenesis in relation to cardiac structure and function

Mendelian randomization provides a multi-omics perspective on the regulation of genes involved in ribosome biogenesis in relation to cardiac structure and function

Abstract Background Ribosome biogenesis (RiboSis) is a complex process for generating ribosomes, the cellular machinery responsible for protein synthesis. Dysfunctional RiboSis can disrupt cardiac structure and function, contributing to cardiovascular diseases. This study employed a Mendelian random...

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Bibliographic Details
Main Authors: Shuxu Wei, Ronghuai Shen, Xiaojia Lu, Xinyi Li, Lingbin He, Youti Zhang, Jiahang Yang, Zhouwu Shu, Xianxi Huang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Clinical Epigenetics
Subjects:
Ribosome biogenesis
Cardiac structure and function
Mendelian randomization
Multi-omics
Online Access:https://doi.org/10.1186/s13148-025-01850-y
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https://doi.org/10.1186/s13148-025-01850-y

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