Streptococcus salivarius-derived ilexgenin A alleviates pneumonia through the gut-lung axis

Streptococcus salivarius-derived ilexgenin A alleviates pneumonia through the gut-lung axis

ABSTRACT The alteration of gut microbiota during critical illness is associated with adverse clinical outcomes. This connection between intestinal dysbiosis and poor outcomes has prompted the idea that restoring healthy microbial communities could offer a novel approach to life-support treatment for...

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Main Authors: Xintao Huang, Rong Wu, Xiaoqi Liang, Zhichao Yu, Ping Qin, Ze Wang, Peiheng Guo, Yunong Zeng, Zhengzheng Yan, Wei Xiao, Yun Ma
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:mSystems
Subjects:
Pseudomonas aeruginosa
pneumonia
gut microbiota
Streptococcus salivarius
ilexgenin A
TLR4
Online Access:https://journals.asm.org/doi/10.1128/msystems.00731-25
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https://journals.asm.org/doi/10.1128/msystems.00731-25

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