Osteoarthritis: modern aspects of pathogenesis, focus on low-intensity inflammation

Osteoarthritis (OA) is the most common disease of the musculoskeletal system. Protein complex, the NLRP3 inflammasome plays the key role in the pathogenesis of OA. It consists of three components: the sensor – NLRP3, the adaptor – ASC and the effector – caspase. Activation of the NLRP3 inflammasome...

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Bibliographic Details
Main Authors: I. S. Svintsitskaya, D. S. Aganov, K. V. Raimuev, A. S. Merlushkina, M. M. Toporkov, A. I. Zhigulina
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2025-04-01
Series:Современная ревматология
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Online Access:https://mrj.ima-press.net/mrj/article/view/1751
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