Relationship between Ca2+ and cAMP as second messengers in ACTH-induced cortisol production in bovine adrenal fasciculata cells

Relationship between Ca2+ and cAMP as second messengers in ACTH-induced cortisol production in bovine adrenal fasciculata cells

In adrenal fasciculata cells stimulated by ACTH, Ca2+ and cAMP play indispensable roles as second messengers in cortisol production. However, whether their second messengers cooperatively or independently participate in steroid production remains unclear. We focused on the roles of Ca2+ and cAMP in...

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Bibliographic Details
Main Authors: Masahiko Kutsukake, Naoko Kuwabara, Yoshikazu Miyate, Kenzo Kudo, Shoko Goto, Eiichi Taira, Eiichi Tachikawa
Format: Article
Language:English
Published: The Japan Endocrine Society 2023-12-01
Series:Endocrine Journal
Subjects:
ca2+
camp
cortisol production
adrenal fasciculata cell
second messenger
Online Access:https://www.jstage.jst.go.jp/article/endocrj/70/12/70_EJ23-0253/_html/-char/en
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https://www.jstage.jst.go.jp/article/endocrj/70/12/70_EJ23-0253/_html/-char/en

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