Chitosan-based multimodal polymeric nanoparticles targeting pancreatic β-cells

Chitosan-based multimodal polymeric nanoparticles targeting pancreatic β-cells

Multimodal in vivo imaging of pancreatic islets might improve monitoring of endocrine grafts upon implantation, helping clinical validation of new regenerative therapies based on the replacement of β-cells in type 1 diabetes affected patients. Herein, the generation of chitosan-based multimodal diag...

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Main Authors: Lorenzo Rossi, Cataldo Pignatelli, Krisztina Kerekes, Francesca Cadamuro, András Dinnyés, Felix Lindheimer, Jochen Seissler, Magdalena Lindner, Sibylle Ziegler, Peter Bartenstein, Yi Qiu, Judit Kovács-Kocsi, Zoltán Körhegyi, Magdolna Bodnár, Erika Fazekas, Eszter Prépost, Francesco Nicotra, Laura Russo
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Carbohydrate Polymer Technologies and Applications
Subjects:
Chitosan
GLP-1R targeting
Beta-cell targeting
Exendin-4
Multimodal imaging
Diagnostic nanoparticles
Online Access:http://www.sciencedirect.com/science/article/pii/S2666893924001907
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