Genetic prediction of immune cells, inflammatory proteins, and metabolite-mediated association between gut microbiota and COPD: a Mendelian randomization study

Abstract Observational studies have suggested a potential association between the gut microbiota and chronic obstructive pulmonary disease (COPD); however, the causal relationship between them, as well as the mediating roles of metabolites, inflammatory proteins, and immune cells, remain unclear. Th...

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Bibliographic Details
Main Authors: Guanglei Chen, Yaxian Jin, Cancan Chu, Yuhao Zheng, Changfu Yang, Yunzhi Chen, Xing Zhu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-05290-9
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