Stepwise response-guided treatment protocol superior to thrombopoietin receptor agonist-based second-line therapy for severe persistent/chronic immune thrombocytopenia: a multicenter prospective study from China

Background: The first second-line international recommendation for children with severe persistent/chronic immune thrombocytopenia is thrombopoietin receptor agonist (TPO-RA)-based treatment; however, <30% can achieve sustained response off-treatment (SRoT), leading to a heavy medical burden. Obj...

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Bibliographic Details
Main Authors: Lingling Fu, Xi Lin, Zhenping Chen, Zhifa Wang, Yan Liu, Lijuan Wang, Yu Hu, Jingyao Ma, Nan Wang, Xiaoling Cheng, Jie Ma, Runhui Wu
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Research and Practice in Thrombosis and Haemostasis
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Online Access:http://www.sciencedirect.com/science/article/pii/S2475037925000263
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