Insights into the effects of apelin-13 on renal function and NHE3 activity following ischemia/reperfusion-induced acute kidney injury

IntroductionAcute kidney injury (AKI) is a clinical syndrome characterized by rapid decline in renal function with varying severity. In this context, tubular function is impaired in ischemia-induced AKI. Although there are no effective therapies for AKI, many compounds have been reported to reduce k...

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Bibliographic Details
Main Authors: Guilherme Lopes-Gonçalves, Juliana Martins Costa-Pessoa, Mariana Charleaux de Ponte, Heitor Macedo Braz, Maria Oliveira-Souza
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1544274/full
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