Computational screening for novel α-glucosidase inhibitory peptides from Chlamys nobilis adductor muscle as a potential antidiabetic agent

Computational screening for novel α-glucosidase inhibitory peptides from Chlamys nobilis adductor muscle as a potential antidiabetic agent

IntroductionThis study aimed to evaluate the adjuvant hypoglycemic function of enzyme hydrolyzate (EHCA) from Chlamys nobilis in mice and to identify α-glucosidase inhibitory peptides.MethodsThe α-glucosidase inhibitory and radical scavenging ability of EHCA were determined in vitro, and the effects...

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Bibliographic Details
Main Authors: Haisheng Lin, Wen Wang, Lei Du, Jialong Gao, Wenhong Cao, Huina Zheng, Zhongqin Chen, Xiaoming Qin, Yuanwei Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Nutrition
Subjects:
Chlamys nobilis
α-Glucosidase inhibitory peptides
molecular docking
glucose tolerance
antioxidant activity
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1566107/full
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https://www.frontiersin.org/articles/10.3389/fnut.2025.1566107/full

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