TNFAIP2 deficiency drives formation of an immunosuppressive tumor microenvironment and confers resistance to anti-PD-1 therapy in skin cutaneous melanoma

Abstract TNFα-induced protein 2 (TNFAIP2) reportedly plays a significant role in the initiation and progression of malignancy. However, its function in skin cutaneous melanoma (SKCM) is largely unknown and urgently needs to be explored. Analysis of a publicly available database revealed that TNFAIP2...

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Bibliographic Details
Main Authors: Yaning Wang, Jinsong Wang, Zhihong Chen, Chiyang Zhong, Hao Luo, Teng Xu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-10952-9
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