Structure activity relationship of dendrimer microbicides with dual action antiviral activity.

Structure activity relationship of dendrimer microbicides with dual action antiviral activity.

<h4>Background</h4>Topical microbicides, used by women to prevent the transmission of HIV and other sexually transmitted infections are urgently required. Dendrimers are highly branched nanoparticles being developed as microbicides. However, the anti-HIV and HSV structure-activity relati...

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Main Authors: David Tyssen, Scott A Henderson, Adam Johnson, Jasminka Sterjovski, Katie Moore, Jennifer La, Mark Zanin, Secondo Sonza, Peter Karellas, Michael P Giannis, Guy Krippner, Steve Wesselingh, Tom McCarthy, Paul R Gorry, Paul A Ramsland, Richard Cone, Jeremy R A Paull, Gareth R Lewis, Gilda Tachedjian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0012309&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0012309&type=printable

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